Her2 3+意思

"Her2 3+" is a term used in pathology to describe the status of a protein called human epidermal growth factor receptor 2 (HER2) in breast cancer cells. HER2 is a protein that is found on the surface of some cancer cells, including breast cancer cells. The term "Her2 3+" means that the cancer cells have a high level of HER2 protein, which is considered an overexpression of the protein.

In breast cancer, HER2 status is determined by testing a sample of the cancer tissue. The results of the test are typically reported as follows:

• Her2 0: No HER2 protein is detected on the cancer cells.
• Her2 1+: Low levels of HER2 protein are detected on the cancer cells.
• Her2 2+: Intermediate levels of HER2 protein are detected on the cancer cells.
• Her2 3+: High levels of HER2 protein are detected on the cancer cells.

A Her2 3+ result is significant because it means that the cancer is likely to respond to treatments that target the HER2 protein, such as trastuzumab (Herceptin) and pertuzumab (Perjeta). These treatments can help to slow the growth of the cancer and improve the outlook for people with HER2-positive breast cancer.